Protein profile

KP13_04770

Signal transduction protein pmrD

Genome: KpKP13

Gene: pmrD AHE43733.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GVP7
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Amino acids 81
Annotations 0
Features 4
PDB binders 0
Druggability 0.03

Overview

Basic information about this protein and its source genome.

Accession
KP13_04770
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
pmrD AHE43733.1
Status
annotated
Amino acids
81
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
87.04

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.03
Structure A0A0H3GVP7
Pocket Pocket 4
P2Rank 0.178
Structure A0A0H3GVP7
Pocket Pocket 1
ColabFold model
FPocket 0.336 · Pocket 2
P2Rank 0.151 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 8 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
1 81 Gene3D G3DSA:2.40.50.650 -
1 81 InterPro IPR038679 Signal transduction protein PmrD superfamily
1 81 Pfam PF11183 Polymyxin resistance protein PmrD
1 81 InterPro IPR044854 Signal transduction protein PmrD

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GVP7
AlphaFold — — full sequence — Viewing
ColabFold KP13_04770
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.09 0.165