Protein profile

KP13_04786

hypothetical protein

Genome: KpKP13

Gene: AHE43749.1 Structure source: AlphaFold + ColabFold UniProt A0A2J5KBS0
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Amino acids 316
Annotations 2
Features 6
PDB binders 0
Druggability 0.315

Overview

Basic information about this protein and its source genome.

Accession
KP13_04786
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43749.1
Status
annotated
Amino acids
316
Structure source
AlphaFold + ColabFold
GO
GO:0016779 Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor). GO:0051607 Reactions triggered in response to the presence of a virus that act to protect the cell or organism.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
92.32

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.315
Structure A0A2J5KBS0
Pocket Pocket 4
P2Rank 0.701
Structure A0A2J5KBS0
Pocket Pocket 1
ColabFold model
FPocket 0.525 · Pocket 2
P2Rank 0.728 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0016779 Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor).
  • GO:0051607 Reactions triggered in response to the presence of a virus that act to protect the cell or organism.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
17 185 CDD cd05400 NT_2-5OAS_ClassI-CCAase
17 185 InterPro IPR006116 2-5OAS/ClassI-CCAase, nucleotidyltransferase domain
18 146 Gene3D G3DSA:3.30.460.10 Beta Polymerase, domain 2
18 146 InterPro IPR043519 Nucleotidyltransferase superfamily
17 76 SUPERFAMILY SSF81301 Nucleotidyltransferase
17 76 InterPro IPR043519 Nucleotidyltransferase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A2J5KBS0
AlphaFold — — full sequence — Viewing
ColabFold KP13_04786
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.315

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 9.18 0.492
2 2.58 0.073
3 2.25 0.056