Protein profile

KP13_04791

hypothetical protein

Genome: KpKP13

Gene: AHE43754.1 Structure source: AlphaFold + ColabFold UniProt A0A5D3JYU5
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Amino acids 153
Annotations 3
Features 8
PDB binders 0
Druggability 0.177

Overview

Basic information about this protein and its source genome.

Accession
KP13_04791
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43754.1
Status
annotated
Amino acids
153
Structure source
AlphaFold + ColabFold
GO
GO:0046872 Binding to a metal ion. GO:0008237 Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0006508 The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
96.62

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.177
Structure A0A5D3JYU5
Pocket Pocket 7
P2Rank 0.499
Structure A0A5D3JYU5
Pocket Pocket 1
ColabFold model
FPocket 0.274 · Pocket 4
P2Rank 0.535 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 2 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0046872 Binding to a metal ion.
  • GO:0008237 Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
  • GO:0006508 The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
18 145 Gene3D G3DSA:3.40.140.10 Cytidine Deaminase, domain 2
1 153 PIRSF PIRSF028170 UCP028170
1 153 InterPro IPR011952 CD-NTase-associated protein 3
36 120 SUPERFAMILY SSF102712 JAB1/MPN domain
36 134 Pfam PF14464 Prokaryotic homologs of the JAB domain
36 134 InterPro IPR028090 JAB domain, prokaryotic
21 151 NCBIfam TIGR02256 conserved hypothetical protein
21 151 InterPro IPR011952 CD-NTase-associated protein 3

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A5D3JYU5
AlphaFold — — full sequence — Viewing
ColabFold KP13_04791
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.04 0.298
2 2.4 0.064