Protein profile

KP13_04799

putative MobB mobilization protein

Genome: KpKP13

Gene: AHE43763.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GQI1
Export view
Amino acids 629
Annotations 0
Features 23
PDB binders 0
Druggability 0.642

Overview

Basic information about this protein and its source genome.

Accession
KP13_04799
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43763.1
Status
annotated
Amino acids
629
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
84.94

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.642
Structure A0A0H3GQI1
Pocket Pocket 10
P2Rank 0.848
Structure A0A0H3GQI1
Pocket Pocket 1
ColabFold model
FPocket 0.667 · Pocket 36
P2Rank 0.877 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 10 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

23 records
Show feature table
Start End DB Term Name
201 240 CDD cd01127 TrwB_TraG_TraD_VirD4
105 125 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
126 629 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
94 104 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
69 91 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
306 567 Gene3D G3DSA:3.40.50.300 -
306 567 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
7 621 PIRSF PIRSF003273 Mobilization_A
7 621 InterPro IPR016387 Mobilization, MobA
172 291 Gene3D G3DSA:3.40.50.300 -
172 291 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
1 11 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
69 93 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
34 38 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
58 68 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
425 526 Pfam PF12696 TraM recognition site of TraD and TraG
425 526 InterPro IPR032689 TraD/TraG, TraM recognition site
12 34 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
39 57 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
12 33 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
104 126 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
169 545 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
169 545 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GQI1
AlphaFold — — full sequence — Viewing
ColabFold KP13_04799
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
10 0.642
6 0.454

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 14.41 0.722
2 2.32 0.059
3 1.61 0.026
4 1.58 0.024
5 0.97 0.005