Protein profile

KP13_04819

hypothetical protein

Genome: KpKP13

Gene: AHE43785.1 Structure source: AlphaFold + ColabFold UniProt A0A1Y0Q1B4
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Amino acids 61
Annotations 0
Features 4
PDB binders 0
Druggability 0.15

Overview

Basic information about this protein and its source genome.

Accession
KP13_04819
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43785.1
Status
annotated
Amino acids
61
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
83.871
DEG E-value
3.09e-33
Localization
Unknown
ColabFold pLDDT
94.07

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.15
Structure A0A1Y0Q1B4
Pocket Pocket 6
P2Rank
Structure A0A1Y0Q1B4
Pocket No pockets
ColabFold model
FPocket 0.047 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 17 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
5 54 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA)
5 54 InterPro IPR010260 DNA-binding transcriptional activator AlpA
2 57 PANTHER PTHR36154 DNA-BINDING TRANSCRIPTIONAL ACTIVATOR ALPA
5 61 Gene3D G3DSA:1.10.238.160 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A1Y0Q1B4 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A1Y0Q1B4
AlphaFold — — full sequence — Viewing
ColabFold KP13_04819
ColabFold — — full sequence — Loaded