Protein profile

KP13_04832

hypothetical protein

Genome: KpKP13

Gene: AHE43799.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GS99
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Amino acids 420
Annotations 3
Features 18
PDB binders 0
Druggability 0.02

Overview

Basic information about this protein and its source genome.

Accession
KP13_04832
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43799.1
Status
annotated
Amino acids
420
Structure source
AlphaFold + ColabFold
GO
GO:0006310 Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0015074 The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
89.41

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.02
Structure A0A0H3GS99
Pocket Pocket 1
P2Rank 0.399
Structure A0A0H3GS99
Pocket Pocket 1
ColabFold model
FPocket 0.378 · Pocket 26
P2Rank 0.177 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 63 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0006310 Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
  • GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
  • GO:0015074 The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
96 176 ProSiteProfiles PS51900 Core-binding (CB) domain profile.
96 176 InterPro IPR044068 Core-binding (CB) domain
1 87 Gene3D G3DSA:3.30.160.390 -
1 87 InterPro IPR038488 Integrase, DNA-binding domain superfamily
201 398 Gene3D G3DSA:1.10.443.10 Intergrase catalytic core
201 398 InterPro IPR013762 Integrase-like, catalytic domain superfamily
199 393 ProSiteProfiles PS51898 Tyrosine recombinase domain profile.
199 393 InterPro IPR002104 Integrase, catalytic domain
226 400 CDD cd00801 INT_P4_C
225 383 Pfam PF00589 Phage integrase family
225 383 InterPro IPR002104 Integrase, catalytic domain
1 408 PANTHER PTHR30629 PROPHAGE INTEGRASE
89 200 Gene3D G3DSA:1.10.150.130 -
89 200 InterPro IPR010998 Integrase/recombinase, N-terminal
98 392 SUPERFAMILY SSF56349 DNA breaking-rejoining enzymes
98 392 InterPro IPR011010 DNA breaking-rejoining enzyme, catalytic core
3 87 Pfam PF13356 Arm DNA-binding domain
3 87 InterPro IPR025166 Integrase, DNA-binding domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GS99
AlphaFold — — full sequence — Viewing
ColabFold KP13_04832
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 5.38 0.255
2 2.91 0.093
3 1.9 0.038