Protein profile

KP13_01633

hypothetical protein

Genome: KpKP13

Gene: AHE43845.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GVH9
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Amino acids 189
Annotations 1
Features 11
PDB binders 0
Druggability 0.601

Overview

Basic information about this protein and its source genome.

Accession
KP13_01633
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43845.1
Status
annotated
Amino acids
189
Structure source
AlphaFold + ColabFold
GO
GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
93.96

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.601
Structure A0A0H3GVH9
Pocket Pocket 6
P2Rank 0.94
Structure A0A0H3GVH9
Pocket Pocket 1
ColabFold model
FPocket 0.537 · Pocket 1
P2Rank 0.941 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 96 / 4744 genomes with a hit
Normalized 0.02

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
1 187 Gene3D G3DSA:3.10.180.10 -
1 187 InterPro IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
1 188 FunFam G3DSA:3.10.180.10:FF:000005 YecM family protein
2 186 SUPERFAMILY SSF54593 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
2 186 InterPro IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
16 186 CDD cd07268 VOC_EcYecM_like
16 186 InterPro IPR010393 Protein of unknown function DUF991, YecM-like
10 185 Pfam PF06185 YecM protein
10 185 InterPro IPR010393 Protein of unknown function DUF991, YecM-like
1 187 PANTHER PTHR37519 -
1 187 InterPro IPR010393 Protein of unknown function DUF991, YecM-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GVH9
AlphaFold — — full sequence — Viewing
ColabFold KP13_01633
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
6 0.601
1 0.507
5 0.008
2 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 37.87 0.94