Protein profile

KP13_01517

Cold-shock DNA-binding domain-containing protein

Genome: KpKP13

Gene: AHE43954.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GPV3
Export view
Amino acids 160
Annotations 1
Features 10
PDB binders 0
Druggability 0.295

Overview

Basic information about this protein and its source genome.

Accession
KP13_01517
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43954.1
Status
annotated
Amino acids
160
Structure source
AlphaFold + ColabFold
GO
GO:0003676 Binding to a nucleic acid.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
74.87

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.295
Structure A0A0H3GPV3
Pocket Pocket 4
P2Rank
Structure A0A0H3GPV3
Pocket No pockets
ColabFold model
FPocket 0.43 · Pocket 2
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 99 / 4744 genomes with a hit
Normalized 0.021

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
2 64 ProSiteProfiles PS51857 Cold-shock (CSD) domain profile.
2 64 InterPro IPR002059 Cold-shock protein, DNA-binding
3 64 CDD cd04458 CSP_CDS
3 64 InterPro IPR002059 Cold-shock protein, DNA-binding
1 72 Gene3D G3DSA:2.40.50.140 -
1 72 InterPro IPR012340 Nucleic acid-binding, OB-fold
4 64 Pfam PF00313 'Cold-shock' DNA-binding domain
4 64 InterPro IPR002059 Cold-shock protein, DNA-binding
3 65 SUPERFAMILY SSF50249 Nucleic acid-binding proteins
3 65 InterPro IPR012340 Nucleic acid-binding, OB-fold

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GPV3
AlphaFold — — full sequence — Viewing
ColabFold KP13_01517
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.295