Protein profile

KP13_01510

putative type VI secretion protein

Genome: KpKP13

Gene: AHE43959.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GPU7
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Amino acids 455
Annotations 0
Features 6
PDB binders 0
Druggability 0.302

Overview

Basic information about this protein and its source genome.

Accession
KP13_01510
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43959.1
Status
annotated
Amino acids
455
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
88.59

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.302
Structure A0A0H3GPU7
Pocket Pocket 35
P2Rank 0.491
Structure A0A0H3GPU7
Pocket Pocket 1
ColabFold model
FPocket 0.476 · Pocket 31
P2Rank 0.079 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 61 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
27 452 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE
27 452 InterPro IPR010263 Type VI secretion system TssK
14 452 NCBIfam TIGR03353 type VI secretion system baseplate subunit TssK
14 452 InterPro IPR010263 Type VI secretion system TssK
13 455 PANTHER PTHR35566 BLR3599 PROTEIN
13 455 InterPro IPR010263 Type VI secretion system TssK

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GPU7
AlphaFold — — full sequence — Viewing
ColabFold KP13_01510
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
35 0.302

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 7.23 0.376
2 1.1 0.008