Protein profile

KP13_01501

pyocin domain-containing protein

Genome: KpKP13

Gene: AHE43966.1 Structure source: AlphaFold + ColabFold UniProt A0A9Q4RSJ6
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Amino acids 296
Annotations 0
Features 6
PDB binders 0
Druggability 0.162

Overview

Basic information about this protein and its source genome.

Accession
KP13_01501
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE43966.1
Status
annotated
Amino acids
296
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
73.1

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.162
Structure A0A9Q4RSJ6
Pocket Pocket 22
P2Rank 0.711
Structure A0A9Q4RSJ6
Pocket Pocket 1
ColabFold model
FPocket 0.166 · Pocket 20
P2Rank 0.084 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 3 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
68 91 MobiDBLite mobidb-lite consensus disorder prediction
1 150 Pfam PF06958 S-type Pyocin
1 150 InterPro IPR016128 Pyosin/cloacin translocation domain
68 84 MobiDBLite mobidb-lite consensus disorder prediction
90 153 SUPERFAMILY SSF69369 Cloacin translocation domain
90 153 InterPro IPR036302 Pyosin/cloacin translocation domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A9Q4RSJ6
AlphaFold — — full sequence — Viewing
ColabFold KP13_01501
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 13.73 0.697
2 3.22 0.111
3 1.62 0.026