Protein profile

KP13_01477

Type VI secretion system domain-containing protein

Genome: KpKP13

Gene: AHE43989.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GPR4

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Amino acids 162

Annotations 0

Features 8

PDB binders 0

Druggability 0.207

Overview

Basic information about this protein and its source genome.

Accession: KP13_01477
Assembly: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene: AHE43989.1
Status: annotated
Amino acids: 162
Structure source: AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Human identity (%): 0.0
Gut microbiome off-target: hit
Essential (DEG): N
DEG identity (%): 0.0
Localization: Unknown
ColabFold pLDDT: 88.16

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.207

Structure A0A0H3GPR4

Pocket Pocket 3

P2Rank

Structure A0A0H3GPR4

Pocket No pockets

ColabFold model

FPocket 0.183 · Pocket 6

Core conservation Conserved core gene

Roary core

CoreCruncher core

Gut microbiome 43 / 4744 genomes with a hit

Normalized 0.009

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
2	156	PANTHER	PTHR37625	OUTER MEMBRANE LIPOPROTEIN-RELATED
2	156	InterPro	IPR017734	Type VI secretion system, lipoprotein SciN
2	138	NCBIfam	TIGR03352	type VI secretion system lipoprotein TssJ
2	138	InterPro	IPR017734	Type VI secretion system, lipoprotein SciN
29	162	Gene3D	G3DSA:2.60.40.4150	Type VI secretion system, lipoprotein SciN
29	162	InterPro	IPR038706	Type VI secretion protein SciN-like superfamily
31	151	Pfam	PF12790	Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113
31	151	InterPro	IPR017734	Type VI secretion system, lipoprotein SciN

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold AF_A0A0H3GPR4	AlphaFold	—	—	full sequence	—	Viewing
ColabFold KP13_01477	ColabFold	—	—	full sequence	—	Loaded

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
3				0.207