Protein profile

KP13_01457

Cation transport regulator chaB

Genome: KpKP13

Gene: AHE44009.1 chaB Structure source: AlphaFold + ColabFold UniProt A0A0H3GPP9
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Amino acids 83
Annotations 0
Features 6
PDB binders 0
Druggability 0.152

Overview

Basic information about this protein and its source genome.

Accession
KP13_01457
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44009.1 chaB
Status
annotated
Amino acids
83
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
53.947
DEG E-value
1.62e-23
Localization
Unknown
ColabFold pLDDT
80.98

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.152
Structure A0A0H3GPP9
Pocket Pocket 1
P2Rank 0.006
Structure A0A0H3GPP9
Pocket Pocket 1
ColabFold model
FPocket 0.192 · Pocket 1
P2Rank 0.05 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 68 / 4744 genomes with a hit
Normalized 0.014

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
16 82 Pfam PF06150 ChaB
16 82 InterPro IPR009317 ChaB
9 82 SUPERFAMILY SSF140376 ChaB-like
9 82 InterPro IPR037205 ChaB superfamily
9 83 Gene3D G3DSA:1.10.1740.70 ChaB
9 83 InterPro IPR037205 ChaB superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GPP9
AlphaFold — — full sequence — Viewing
ColabFold KP13_01457
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer