Protein profile

KP13_04682

hypothetical protein

Genome: KpKP13

Gene: AHE44059.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GZG8
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Amino acids 94
Annotations 1
Features 4
PDB binders 0
Druggability 0.291

Overview

Basic information about this protein and its source genome.

Accession
KP13_04682
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44059.1
Status
annotated
Amino acids
94
Structure source
AlphaFold + ColabFold
GO
GO:0004521 Catalysis of the cleavage of ester linkages within ribonucleic acid by creating internal breaks.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
50.562
DEG E-value
4.06e-31
Localization
Unknown
ColabFold pLDDT
92.43

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.291
Structure A0A0H3GZG8
Pocket Pocket 1
P2Rank
Structure A0A0H3GZG8
Pocket No pockets
ColabFold model
FPocket 0.031 · Pocket 3
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 41 / 4744 genomes with a hit
Normalized 0.009

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0004521 Catalysis of the cleavage of ester linkages within ribonucleic acid by creating internal breaks.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
7 94 Gene3D G3DSA:3.30.70.2360 -
7 94 InterPro IPR038241 Endoribonuclease antitoxin GhoS superfamily
2 92 Pfam PF11080 Endoribonuclease GhoS
2 92 InterPro IPR022597 Endoribonuclease antitoxin GhoS

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GZG8
AlphaFold — — full sequence — Viewing
ColabFold KP13_04682
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.291