Protein profile

KP13_04651

hypothetical protein

Genome: KpKP13

Gene: AHE44089.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GZE9
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Amino acids 106
Annotations 0
Features 9
PDB binders 0
Druggability 0.061

Overview

Basic information about this protein and its source genome.

Accession
KP13_04651
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44089.1
Status
annotated
Amino acids
106
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
69.6

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.061
Structure A0A0H3GZE9
Pocket Pocket 1
P2Rank
Structure A0A0H3GZE9
Pocket No pockets
ColabFold model
FPocket 0.087 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 6 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
22 106 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
16 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 21 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
32 51 MobiDBLite mobidb-lite consensus disorder prediction
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 21 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 19 SignalP_EUK SignalP-noTM SignalP-noTM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GZE9 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GZE9
AlphaFold — — full sequence — Viewing
ColabFold KP13_04651
ColabFold — — full sequence — Loaded