Protein profile

KP13_04648

hypothetical protein

Genome: KpKP13

Gene: AHE44092.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GR88
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Amino acids 326
Annotations 0
Features 4
PDB binders 0
Druggability 0.223

Overview

Basic information about this protein and its source genome.

Accession
KP13_04648
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44092.1
Status
annotated
Amino acids
326
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
73.926
DEG E-value
0.0
Localization
Unknown
ColabFold pLDDT
92.98

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.223
Structure A0A0H3GR88
Pocket Pocket 21
P2Rank 0.671
Structure A0A0H3GR88
Pocket Pocket 1
ColabFold model
FPocket 0.532 · Pocket 16
P2Rank 0.683 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 87 / 4744 genomes with a hit
Normalized 0.018

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
1 325 PIRSF PIRSF034367 UCP034367
1 325 InterPro IPR015004 MesX
1 321 Pfam PF08908 Putative oxygenase MesX
1 321 InterPro IPR015004 MesX

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GR88
AlphaFold — — full sequence — Viewing
ColabFold KP13_04648
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
21 0.223

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 7.45 0.391
2 4.32 0.18
3 2.3 0.058
4 1.53 0.023
5 1.25 0.012