Protein profile

KP13_05313

Gluconate 2-dehydrogenase subunit 3

Genome: KpKP13

Gene: AHE44169.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GUP8
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Amino acids 276
Annotations 0
Features 2
PDB binders 0
Druggability 0.222

Overview

Basic information about this protein and its source genome.

Accession
KP13_05313
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44169.1
Status
annotated
Amino acids
276
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
79.21

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.222
Structure A0A0H3GUP8
Pocket Pocket 7
P2Rank 0.028
Structure A0A0H3GUP8
Pocket Pocket 1
ColabFold model
FPocket 0.349 · Pocket 5
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 36 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

2 records
Show feature table
Start End DB Term Name
95 249 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3
95 249 InterPro IPR027056 Gluconate 2-dehydrogenase subunit 3

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GUP8
AlphaFold — — full sequence — Viewing
ColabFold KP13_05313
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
7 0.222

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.31 0.014