Protein profile

KP13_05111

hypothetical protein

Genome: KpKP13

Gene: AHE44229.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GQV8
Amino acids 175
Annotations 0
Features 14
PDB binders 0
Druggability 0.101

Overview

Basic information about this protein and its source genome.

Accession
KP13_05111
Gene
AHE44229.1
Status
annotated
Amino acids
175
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
71.84

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.101
Structure A0A0H3GQV8
Pocket Pocket 3
P2Rank
Structure A0A0H3GQV8
Pocket No pockets
ColabFold model
FPocket 0.022 · Pocket 5
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 48 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
66 88 MobiDBLite mobidb-lite consensus disorder prediction
32 88 MobiDBLite mobidb-lite consensus disorder prediction
76 175 Gene3D G3DSA:3.10.450.160 inner membrane protein cigr
10 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
27 175 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 26 SignalP_EUK SignalP-noTM SignalP-noTM
1 26 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 26 Phobius SIGNAL_PEPTIDE Signal peptide region
22 26 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
152 174 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
7 26 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
9 175 NCBIfam NF040487 anti-virulence regulator CigR family protein
32 65 MobiDBLite mobidb-lite consensus disorder prediction
1 9 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GQV8 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GQV8
AlphaFold full sequence Viewing
ColabFold KP13_05111
ColabFold full sequence Loaded