Protein profile

KP13_05123

hypothetical protein

Genome: KpKP13

Gene: AHE44241.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GUJ0
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Amino acids 69
Annotations 0
Features 14
PDB binders 0
Druggability 0.007

Overview

Basic information about this protein and its source genome.

Accession
KP13_05123
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44241.1
Status
annotated
Amino acids
69
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
46.154
DEG E-value
6.65e-15
Localization
Unknown
ColabFold pLDDT
80.65

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.007
Structure A0A0H3GUJ0
Pocket Pocket 1
P2Rank
Structure A0A0H3GUJ0
Pocket No pockets
ColabFold model
FPocket 0.632 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 66 / 4744 genomes with a hit
Normalized 0.014

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
18 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 5 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
7 29 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 29 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 22 SignalP_EUK SignalP-noTM SignalP-noTM
23 69 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
6 17 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
18 69 Gene3D G3DSA:3.30.1660.10 -
18 69 InterPro IPR025543 Dodecin-like
3 67 SUPERFAMILY SSF159871 YdgH-like
3 67 InterPro IPR036275 YdgH-like superfamily
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
24 67 Pfam PF07338 YdgH/BhsA/McbA-like domain
24 67 InterPro IPR010854 YdgH/BhsA/McbA-like domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GUJ0
AlphaFold — — full sequence — Viewing
ColabFold KP13_05123
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer