Protein profile

KP13_05134

Acid shock protein

Genome: KpKP13

Gene: AHE44253.1 Structure source: AlphaFold + ColabFold UniProt A0A1C1G9E4
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Amino acids 116
Annotations 1
Features 12
PDB binders 0
Druggability 0.1

Overview

Basic information about this protein and its source genome.

Accession
KP13_05134
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44253.1
Status
annotated
Amino acids
116
Structure source
AlphaFold + ColabFold
GO
GO:0042597 The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Periplasmic
ColabFold pLDDT
56.74

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.1
Structure A0A1C1G9E4
Pocket Pocket 7
P2Rank
Structure A0A1C1G9E4
Pocket No pockets
ColabFold model
FPocket 0.074 · Pocket 2
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 2 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0042597 The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
1 116 Hamap MF_00546 Acid shock protein [asr].
1 116 InterPro IPR023497 Acid shock protein
22 116 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 21 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
16 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
94 108 MobiDBLite mobidb-lite consensus disorder prediction
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
24 116 MobiDBLite mobidb-lite consensus disorder prediction
1 24 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
55 79 MobiDBLite mobidb-lite consensus disorder prediction

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A1C1G9E4 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A1C1G9E4
AlphaFold — — full sequence — Viewing
ColabFold KP13_05134
ColabFold — — full sequence — Loaded