Protein profile

KP13_04424

OriC-binding nucleoid-associated protein

Genome: KpKP13

Gene: AHE44297.1 cnu Structure source: AlphaFold + ColabFold UniProt A0A0H3GQP8
Export view
Amino acids 89
Annotations 0
Features 6
PDB binders 0
Druggability 0.231

Overview

Basic information about this protein and its source genome.

Accession
KP13_04424
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44297.1 cnu
Status
annotated
Amino acids
89
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
42.254
DEG E-value
6.3e-13
Localization
Unknown
ColabFold pLDDT
77.73

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.231
Structure A0A0H3GQP8
Pocket Pocket 3
P2Rank
Structure A0A0H3GQP8
Pocket No pockets
ColabFold model
FPocket 0.258 · Pocket 3
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 78 / 4744 genomes with a hit
Normalized 0.016

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
19 89 Gene3D G3DSA:1.20.1280.40 HHA
19 89 InterPro IPR036666 HHA superfamily
18 89 SUPERFAMILY SSF68989 Hemolysin expression modulating protein HHA
18 89 InterPro IPR036666 HHA superfamily
27 86 Pfam PF05321 Haemolysin expression modulating protein
27 86 InterPro IPR007985 Haemolysin expression modulating, HHA

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GQP8
AlphaFold — — full sequence — Viewing
ColabFold KP13_04424
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.231