Protein profile

KP13_04451

hypothetical protein

Genome: KpKP13

Gene: AHE44324.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GP23
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Amino acids 222
Annotations 0
Features 11
PDB binders 0
Druggability 0.966

Overview

Basic information about this protein and its source genome.

Accession
KP13_04451
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44324.1
Status
annotated
Amino acids
222
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
71.171
DEG E-value
3.71e-123
Localization
Unknown
ColabFold pLDDT
87.16

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.966
Structure A0A0H3GP23
Pocket Pocket 1
P2Rank 0.905
Structure A0A0H3GP23
Pocket Pocket 1
ColabFold model
FPocket 0.958 · Pocket 1
P2Rank 0.89 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 59 / 4744 genomes with a hit
Normalized 0.012

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
30 213 Pfam PF11769 Protein of unknown function (DUF3313)
30 213 InterPro IPR021747 Protein of unknown function DUF3313
5 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 25 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
19 23 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 23 SignalP_EUK SignalP-noTM SignalP-noTM
24 222 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 23 Phobius SIGNAL_PEPTIDE Signal peptide region
1 22 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 21 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GP23
AlphaFold — — full sequence — Viewing
ColabFold KP13_04451
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.966

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 26.46 0.914
2 7.81 0.414
3 3.83 0.149