Protein profile

KP13_04489

hypothetical protein

Genome: KpKP13

Gene: AHE44363.1 Structure source: AlphaFold + ColabFold UniProt W8UHD3
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Amino acids 209
Annotations 0
Features 5
PDB binders 0
Druggability 0.361

Overview

Basic information about this protein and its source genome.

Accession
KP13_04489
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44363.1
Status
annotated
Amino acids
209
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
86.05

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.361
Structure W8UHD3
Pocket Pocket 9
P2Rank 0.865
Structure W8UHD3
Pocket Pocket 1
ColabFold model
FPocket 0.587 · Pocket 19
P2Rank 0.895 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 37 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records
Show feature table
Start End DB Term Name
27 201 PANTHER PTHR37816 YALI0E33011P
27 196 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
27 196 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
19 133 Gene3D G3DSA:3.40.50.300 -
19 133 InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_W8UHD3
AlphaFold — — full sequence — Viewing
ColabFold KP13_04489
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
9 0.361
1 0.237