Protein profile

KP13_04494

putative acyltransferase

Genome: KpKP13

Gene: AHE44368.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GQF6
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Amino acids 169
Annotations 1
Features 9
PDB binders 0
Druggability 0.113

Overview

Basic information about this protein and its source genome.

Accession
KP13_04494
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44368.1
Status
annotated
Amino acids
169
Structure source
AlphaFold + ColabFold
GO
GO:0016747 Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
92.73

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.113
Structure A0A0H3GQF6
Pocket Pocket 11
P2Rank 0.885
Structure A0A0H3GQF6
Pocket Pocket 1
ColabFold model
FPocket 0.724 · Pocket 2
P2Rank 0.729 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 53 / 4744 genomes with a hit
Normalized 0.011

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016747 Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
53 115 CDD cd04301 NAT_SF
5 137 SUPERFAMILY SSF55729 Acyl-CoA N-acyltransferases (Nat)
5 137 InterPro IPR016181 Acyl-CoA N-acyltransferase
47 142 PANTHER PTHR43877 -
3 162 Gene3D G3DSA:3.40.630.30 -
13 157 ProSiteProfiles PS51186 Gcn5-related N-acetyltransferase (GNAT) domain profile.
13 157 InterPro IPR000182 GNAT domain
33 132 Pfam PF00583 Acetyltransferase (GNAT) family
33 132 InterPro IPR000182 GNAT domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GQF6
AlphaFold — — full sequence — Viewing
ColabFold KP13_04494
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 11.84 0.628
2 4.87 0.218
3 1.55 0.023
4 1.4 0.017
5 1.12 0.008