Protein profile

KP13_04566

hypothetical protein

Genome: KpKP13

Gene: AHE44441.1 Structure source: AlphaFold + ColabFold UniProt A6T9J3
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Amino acids 127
Annotations 0
Features 15
PDB binders 0
Druggability 0.029

Overview

Basic information about this protein and its source genome.

Accession
KP13_04566
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44441.1
Status
annotated
Amino acids
127
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
57.724
DEG E-value
7.8e-51
Localization
Unknown
ColabFold pLDDT
80.75

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.029
Structure A6T9J3
Pocket Pocket 3
P2Rank
Structure A6T9J3
Pocket No pockets
ColabFold model
FPocket 0.34 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 49 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
8 12 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
7 121 PANTHER PTHR36571 PROTEIN YGIW
2 7 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
14 123 Gene3D G3DSA:2.40.50.200 -
14 123 InterPro IPR036700 Bacterial OB-fold superfamily
23 121 SUPERFAMILY SSF101756 Hypothetical protein YgiW
23 121 InterPro IPR036700 Bacterial OB-fold superfamily
13 127 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
23 121 Pfam PF04076 Bacterial OB fold (BOF) protein
23 121 InterPro IPR005220 Bacterial OB-fold
1 12 Phobius SIGNAL_PEPTIDE Signal peptide region
13 121 NCBIfam NF033674 NirD/YgiW/YdeI family stress tolerance protein
5 123 NCBIfam TIGR00156 YgiW/YdeI family stress tolerance OB fold protein
5 123 InterPro IPR016052 YgiW/YdeI

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A6T9J3
AlphaFold — — full sequence — Viewing
ColabFold KP13_04566
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer