Protein profile

KP13_05495

hypothetical protein

Genome: KpKP13

Gene: AHE44501.1 Structure source: AlphaFold + ColabFold UniProt W8UHP5
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Amino acids 149
Annotations 0
Features 13
PDB binders 0
Druggability 0.867

Overview

Basic information about this protein and its source genome.

Accession
KP13_05495
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44501.1
Status
annotated
Amino acids
149
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
92.33

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.867
Structure W8UHP5
Pocket Pocket 1
P2Rank 0.9
Structure W8UHP5
Pocket Pocket 1
ColabFold model
FPocket 0.94 · Pocket 1
P2Rank 0.893 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 49 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
20 148 PANTHER PTHR39203 CYTOPLASMIC PROTEIN-RELATED
20 148 InterPro IPR009326 Protein of unknown function DUF984
12 147 SUPERFAMILY SSF88697 PUA domain-like
12 147 InterPro IPR015947 PUA-like superfamily
27 147 CDD cd06553 ASCH_Ef3133_like
27 147 InterPro IPR009326 Protein of unknown function DUF984
39 147 Pfam PF04266 ASCH domain
39 147 InterPro IPR007374 ASCH domain
12 149 Gene3D G3DSA:3.10.400.10 Sulfate adenylyltransferase
30 147 SMART SM01022 ASCH_2
30 147 InterPro IPR007374 ASCH domain
13 149 PIRSF PIRSF021320 UCP021320
13 149 InterPro IPR009326 Protein of unknown function DUF984

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_W8UHP5
AlphaFold — — full sequence — Viewing
ColabFold KP13_05495
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.867

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 18.94 0.832