Protein profile

KP13_05504

GCN5-related N-acetyltransferase

Genome: KpKP13

Gene: AHE44510.1 Structure source: AlphaFold + ColabFold UniProt W8UHQ6
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Amino acids 142
Annotations 2
Features 9
PDB binders 0
Druggability 0.067

Overview

Basic information about this protein and its source genome.

Accession
KP13_05504
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44510.1
Status
annotated
Amino acids
142
Structure source
AlphaFold + ColabFold
EC
2.3.1.-
GO
GO:0016747 Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
95.01

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.067
Structure W8UHQ6
Pocket Pocket 9
P2Rank 0.499
Structure W8UHQ6
Pocket Pocket 1
ColabFold model
FPocket 0.254 · Pocket 7
P2Rank 0.374 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 10 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 EC 1 GO

Enzyme Commission (EC)

1

Gene Ontology (GO)

1
  • GO:0016747 Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
3 135 SUPERFAMILY SSF55729 Acyl-CoA N-acyltransferases (Nat)
3 135 InterPro IPR016181 Acyl-CoA N-acyltransferase
3 139 PANTHER PTHR43877 -
2 141 Gene3D G3DSA:3.40.630.30 -
40 130 Pfam PF00583 Acetyltransferase (GNAT) family
40 130 InterPro IPR000182 GNAT domain
4 142 ProSiteProfiles PS51186 Gcn5-related N-acetyltransferase (GNAT) domain profile.
4 142 InterPro IPR000182 GNAT domain
47 113 CDD cd04301 NAT_SF

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_W8UHQ6
AlphaFold — — full sequence — Viewing
ColabFold KP13_05504
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.28 0.441
2 3.06 0.101
3 0.87 0.003