Protein profile

KP13_05546

hypothetical protein

Genome: KpKP13

Gene: AHE44552.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GPY4
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Amino acids 251
Annotations 0
Features 10
PDB binders 0
Druggability 0.106

Overview

Basic information about this protein and its source genome.

Accession
KP13_05546
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44552.1
Status
annotated
Amino acids
251
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
42.276
DEG E-value
1.91e-65
Localization
Cytoplasmic
ColabFold pLDDT
97.57

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.106
Structure A0A0H3GPY4
Pocket Pocket 4
P2Rank 0.269
Structure A0A0H3GPY4
Pocket Pocket 1
ColabFold model
FPocket 0.202 · Pocket 2
P2Rank 0.414 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 12 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
55 143 PANTHER PTHR37947 BLL2462 PROTEIN
1 249 Gene3D G3DSA:3.40.50.880 -
1 249 InterPro IPR029062 Class I glutamine amidotransferase-like
4 248 SUPERFAMILY SSF52317 Class I glutamine amidotransferase-like
4 248 InterPro IPR029062 Class I glutamine amidotransferase-like
5 154 CDD cd03143 A4_beta-galactosidase_middle_domain
1 251 PIRSF PIRSF034405 UCP034405
1 251 InterPro IPR017027 STM3548-like
4 248 Pfam PF07090 Putative glutamine amidotransferase
4 248 InterPro IPR010768 Putative glutamine amidotransferase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GPY4
AlphaFold — — full sequence — Viewing
ColabFold KP13_05546
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.61 0.135
2 1.54 0.023