Protein profile

KP13_05553

membrane complex biogenesis protein BtpA-like protein

Genome: KpKP13

Gene: AHE44559.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GNG6
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Amino acids 284
Annotations 0
Features 10
PDB binders 0
Druggability 0.233

Overview

Basic information about this protein and its source genome.

Accession
KP13_05553
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44559.1
Status
annotated
Amino acids
284
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
92.85

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.233
Structure A0A0H3GNG6
Pocket Pocket 4
P2Rank 0.922
Structure A0A0H3GNG6
Pocket Pocket 1
ColabFold model
FPocket 0.582 · Pocket 1
P2Rank 0.939 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 12 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
22 278 Pfam PF03437 BtpA family
22 278 InterPro IPR005137 Membrane complex biogenesis protein, BtpA family
12 277 SUPERFAMILY SSF51366 Ribulose-phoshate binding barrel
12 277 InterPro IPR011060 Ribulose-phosphate binding barrel
13 283 PIRSF PIRSF005956 BtpA
13 283 InterPro IPR005137 Membrane complex biogenesis protein, BtpA family
23 278 NCBIfam TIGR00259 BtpA/SgcQ family protein
23 278 InterPro IPR005137 Membrane complex biogenesis protein, BtpA family
16 278 PANTHER PTHR21381 ZGC:162297
16 278 InterPro IPR005137 Membrane complex biogenesis protein, BtpA family

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GNG6
AlphaFold — — full sequence — Viewing
ColabFold KP13_05553
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.233
12 0.216

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 21.28 0.868