Protein profile

KP13_05252

Putative type VI secretion system effector, Hcp1 family

Genome: KpKP13

Gene: AHE44658.1 Structure source: ColabFold
Export view
Amino acids 126
Annotations 0
Features 9
PDB binders 0
Druggability 0.107

Overview

Basic information about this protein and its source genome.

Accession
KP13_05252
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44658.1
Status
annotated
Amino acids
126
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Extracellular
ColabFold pLDDT
91.32

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.107
Structure CB_KP13_05252
Pocket Pocket 3
P2Rank 0.141
Structure CB_KP13_05252
Pocket Pocket 1
ColabFold model
FPocket 0.107 · Pocket 3
P2Rank 0.141 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 56 / 4744 genomes with a hit
Normalized 0.012

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
1 121 NCBIfam TIGR03344 type VI secretion system tube protein TssD/Hcp
1 121 InterPro IPR008514 Type VI secretion system effector Hcp
19 115 PANTHER PTHR34319 MAJOR EXPORTED PROTEIN
1 126 Gene3D G3DSA:2.30.110.20 -
1 126 InterPro IPR036624 Hcp1-like superfamily
2 108 Pfam PF05638 Type VI secretion system effector, Hcp
2 108 InterPro IPR008514 Type VI secretion system effector Hcp
2 126 SUPERFAMILY SSF141452 Hcp1-like
2 126 InterPro IPR036624 Hcp1-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold KP13_05252
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.12 0.166