Protein profile

KP13_01156

hypothetical protein

Genome: KpKP13

Gene: AHE44738.1 Structure source: AlphaFold + ColabFold UniProt W8UVL7
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Amino acids 108
Annotations 0
Features 9
PDB binders 0
Druggability 0.612

Overview

Basic information about this protein and its source genome.

Accession
KP13_01156
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44738.1
Status
annotated
Amino acids
108
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
64.835
DEG E-value
5.77e-29
Localization
Unknown
ColabFold pLDDT
71.19

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.612
Structure W8UVL7
Pocket Pocket 5
P2Rank
Structure W8UVL7
Pocket No pockets
ColabFold model
FPocket 0.563 · Pocket 4
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 59 / 4744 genomes with a hit
Normalized 0.012

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
34 39 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 39 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 21 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
40 108 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 39 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 39 Phobius SIGNAL_PEPTIDE Signal peptide region
22 33 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
44 97 Pfam PF06649 Protein of unknown function (DUF1161)
44 97 InterPro IPR010595 Protein of unknown function DUF1161

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_W8UVL7
AlphaFold — — full sequence — Viewing
ColabFold KP13_01156
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.612
7 0.48
4 0.336