Protein profile

KP13_01167

Acid shock protein

Genome: KpKP13

Gene: asr AHE44748.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GPG0

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Amino acids 152

Annotations 0

Features 13

PDB binders 0

Druggability 0.712

Overview

Basic information about this protein and its source genome.

Accession: KP13_01167
Assembly: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene: asr AHE44748.1
Status: annotated
Amino acids: 152
Structure source: AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Human identity (%): 0.0
Gut microbiome off-target: No hit
Essential (DEG): N
DEG identity (%): 0.0
Localization: Periplasmic
ColabFold pLDDT: 57.71

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.712

Structure A0A0H3GPG0

Pocket Pocket 2

P2Rank

Structure A0A0H3GPG0

Pocket No pockets

ColabFold model

FPocket 0.502 · Pocket 1

Core conservation Accessory gene

Roary accessory

CoreCruncher accessory

Gut microbiome 0 / 4744 genomes with a hit

Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records

Show feature table

Start	End	DB	Term	Name
14	152	Hamap	MF_00546	Acid shock protein [asr].
14	152	InterPro	IPR023497	Acid shock protein
17	28	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.
1	16	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
17	39	TMHMM	TMhelix	Region of a membrane-bound protein predicted to be embedded in the membrane.
111	142	MobiDBLite	mobidb-lite	consensus disorder prediction
45	152	MobiDBLite	mobidb-lite	consensus disorder prediction
1	34	Phobius	SIGNAL_PEPTIDE	Signal peptide region
29	34	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
72	86	MobiDBLite	mobidb-lite	consensus disorder prediction
1	34	SignalP_GRAM_POSITIVE	SignalP-TM	SignalP-TM
1	34	SignalP_GRAM_NEGATIVE	SignalP-noTM	SignalP-noTM
35	152	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold AF_A0A0H3GPG0	AlphaFold	—	—	full sequence	—	Viewing
ColabFold KP13_01167	ColabFold	—	—	full sequence	—	Loaded

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
2				0.712

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.502