Protein profile

KP13_05025

hypothetical protein

Genome: KpKP13

Gene: AHE44800.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GSA0
Export view
Amino acids 316
Annotations 0
Features 30
PDB binders 0
Druggability 0.04

Overview

Basic information about this protein and its source genome.

Accession
KP13_05025
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44800.1
Status
annotated
Amino acids
316
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
82.73

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.04
Structure A0A0H3GSA0
Pocket Pocket 10
P2Rank 0.086
Structure A0A0H3GSA0
Pocket Pocket 1
ColabFold model
FPocket 0.433 · Pocket 9
P2Rank 0.256 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 106 / 4744 genomes with a hit
Normalized 0.022

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

30 records
Show feature table
Start End DB Term Name
261 316 Pfam PF07338 YdgH/BhsA/McbA-like domain
261 316 InterPro IPR010854 YdgH/BhsA/McbA-like domain
119 174 Pfam PF07338 YdgH/BhsA/McbA-like domain
119 174 InterPro IPR010854 YdgH/BhsA/McbA-like domain
34 90 Pfam PF07338 YdgH/BhsA/McbA-like domain
34 90 InterPro IPR010854 YdgH/BhsA/McbA-like domain
19 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
315 316 Coils Coil Coil
21 90 Gene3D G3DSA:3.30.1660.10 -
21 90 InterPro IPR025543 Dodecin-like
106 174 Gene3D G3DSA:3.30.1660.10 -
106 174 InterPro IPR025543 Dodecin-like
1 22 SignalP_EUK SignalP-noTM SignalP-noTM
245 316 Gene3D G3DSA:3.30.1660.10 -
245 316 InterPro IPR025543 Dodecin-like
3 94 SUPERFAMILY SSF159871 YdgH-like
3 94 InterPro IPR036275 YdgH-like superfamily
23 316 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 316 PANTHER PTHR34156 OUTER MEMBRANE PROTEIN-RELATED-RELATED
7 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 316 PIRSF PIRSF014774 YdgH
1 316 InterPro IPR025539 YdgH protein
241 316 SUPERFAMILY SSF159871 YdgH-like
241 316 InterPro IPR036275 YdgH-like superfamily
1 316 NCBIfam NF040471 DUF1471 family protein YdgH
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
108 177 SUPERFAMILY SSF159871 YdgH-like
108 177 InterPro IPR036275 YdgH-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GSA0
AlphaFold — — full sequence — Viewing
ColabFold KP13_05025
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.81 0.034
2 1.7 0.029