Protein profile

KP13_05004

sirA domain-containing protein

Genome: KpKP13

Gene: AHE44821.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GS76
Export view
Amino acids 77
Annotations 0
Features 11
PDB binders 0
Druggability 0.019

Overview

Basic information about this protein and its source genome.

Accession
KP13_05004
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44821.1
Status
annotated
Amino acids
77
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
62.857
DEG E-value
1.24e-30
Localization
Unknown
ColabFold pLDDT
88.21

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.019
Structure A0A0H3GS76
Pocket Pocket 2
P2Rank
Structure A0A0H3GS76
Pocket No pockets
ColabFold model
FPocket 0.008 · Pocket 2
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 128 / 4744 genomes with a hit
Normalized 0.027

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
9 77 CDD cd03422 YedF
3 77 SUPERFAMILY SSF64307 SirA-like
3 77 InterPro IPR036868 TusA-like domain superfamily
5 77 FunFam G3DSA:3.30.110.40:FF:000001 SirA-like family protein
10 34 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature.
10 34 InterPro IPR001455 TusA-like domain
9 77 Pfam PF01206 Sulfurtransferase TusA
9 77 InterPro IPR001455 TusA-like domain
5 77 Gene3D G3DSA:3.30.110.40 -
5 77 InterPro IPR036868 TusA-like domain superfamily
5 77 PANTHER PTHR33279 SULFUR CARRIER PROTEIN YEDF-RELATED

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GS76 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GS76
AlphaFold — — full sequence — Viewing
ColabFold KP13_05004
ColabFold — — full sequence — Loaded