Protein profile

KP13_05002

putative membrane protein

Genome: KpKP13

Gene: AHE44823.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMN1
Export view
Amino acids 52
Annotations 1
Features 11
PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession
KP13_05002
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44823.1
Status
annotated
Amino acids
52
Structure source
AlphaFold + ColabFold
GO
GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
95.79

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket
Structure A0A0H3GMN1
Pocket No pockets
P2Rank
Structure A0A0H3GMN1
Pocket No pockets
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 83 / 4744 genomes with a hit
Normalized 0.017

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016020 A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
1 22 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
23 48 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
49 52 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
25 47 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
7 22 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature.
7 22 InterPro IPR000612 Proteolipid membrane potential modulator
4 51 PANTHER PTHR21659 HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED
4 51 InterPro IPR000612 Proteolipid membrane potential modulator
3 48 Pfam PF01679 Proteolipid membrane potential modulator
3 48 InterPro IPR000612 Proteolipid membrane potential modulator
2 20 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GMN1 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMN1
AlphaFold — — full sequence — Viewing
ColabFold KP13_05002
ColabFold — — full sequence — Loaded