Protein profile

KP13_04970

Phenylacetic acid degradation protein paaD

Genome: KpKP13

Gene: paaD AHE44857.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMJ6
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Amino acids 165
Annotations 0
Features 9
PDB binders 0
Druggability 0.361

Overview

Basic information about this protein and its source genome.

Accession
KP13_04970
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
paaD AHE44857.1
Status
annotated
Amino acids
165
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
88.63

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.361
Structure A0A0H3GMJ6
Pocket Pocket 2
P2Rank 0.401
Structure A0A0H3GMJ6
Pocket Pocket 1
ColabFold model
FPocket 0.231 · Pocket 3
P2Rank 0.53 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 49 / 4744 genomes with a hit
Normalized 0.01

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
8 107 PANTHER PTHR42831 FE-S PROTEIN MATURATION AUXILIARY FACTOR YITW
14 73 Pfam PF01883 Iron-sulfur cluster assembly protein
14 73 InterPro IPR002744 MIP18 family-like
22 165 NCBIfam TIGR02159 phenylacetate-CoA oxygenase subunit PaaJ
22 165 InterPro IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit
13 105 SUPERFAMILY SSF117916 Fe-S cluster assembly (FSCA) domain-like
13 105 InterPro IPR034904 Fe-S cluster assembly domain superfamily
9 106 Gene3D G3DSA:3.30.300.130 -
9 106 InterPro IPR034904 Fe-S cluster assembly domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMJ6
AlphaFold — — full sequence — Viewing
ColabFold KP13_04970
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.361

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 5.63 0.271
2 1.1 0.008