Protein profile

KP13_04968

Phenylacetic acid degradation protein paaB

Genome: KpKP13

Gene: AHE44859.1 paaB Structure source: Experimental + AlphaFold + ColabFold UniProt A6T8I1
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Amino acids 95
Annotations 0
Features 9
PDB binders 0
Druggability 0.242

Overview

Basic information about this protein and its source genome.

Accession
KP13_04968
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44859.1 paaB
Status
annotated
Amino acids
95
Structure source
Experimental + AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
88.44

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.242
Structure A6T8I1
Pocket Pocket 3
P2Rank
Structure A6T8I1
Pocket No pockets
ColabFold model
FPocket 0.406 · Pocket 3
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 67 / 4744 genomes with a hit
Normalized 0.014

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
2 65 Gene3D G3DSA:3.10.20.520 Phenylacetic acid degradation B
2 65 InterPro IPR038693 Phenylacetyl-CoA epoxidase, subunit B
1 95 PIRSF PIRSF030200 PaaB
1 95 InterPro IPR009359 Phenylacetic acid degradation B
2 65 FunFam G3DSA:3.10.20.520:FF:000001 Phenylacetate-CoA oxygenase, PaaH subunit
6 90 Pfam PF06243 Phenylacetic acid degradation B
6 90 InterPro IPR009359 Phenylacetic acid degradation B
6 95 NCBIfam TIGR02157 1,2-phenylacetyl-CoA epoxidase subunit B
6 95 InterPro IPR009359 Phenylacetic acid degradation B

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 4IIT
X-ray 20.00 Å - —
PDBe RCSB PDBj File
Viewing
AlphaFold AF_A6T8I1
AlphaFold — — full sequence — Loaded
ColabFold KP13_04968
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer