Protein profile

KP13_04361

hypothetical protein

Genome: KpKP13

Gene: AHE44907.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GWK0
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Amino acids 70
Annotations 0
Features 13
PDB binders 0
Druggability 0.174

Overview

Basic information about this protein and its source genome.

Accession
KP13_04361
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44907.1
Status
annotated
Amino acids
70
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
81.54

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.174
Structure A0A0H3GWK0
Pocket Pocket 2
P2Rank
Structure A0A0H3GWK0
Pocket No pockets
ColabFold model
FPocket 0.177 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 6 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
1 22 SignalP_EUK SignalP-noTM SignalP-noTM
1 5 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
6 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
24 68 Pfam PF07338 YdgH/BhsA/McbA-like domain
24 68 InterPro IPR010854 YdgH/BhsA/McbA-like domain
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
23 70 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
17 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
20 68 Gene3D G3DSA:3.30.1660.10 -
20 68 InterPro IPR025543 Dodecin-like
5 68 SUPERFAMILY SSF159871 YdgH-like
5 68 InterPro IPR036275 YdgH-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GWK0 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GWK0
AlphaFold — — full sequence — Viewing
ColabFold KP13_04361
ColabFold — — full sequence — Loaded