Protein profile

KP13_04356

Type VI secretion system protein

Genome: KpKP13

Gene: AHE44913.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GS07
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Amino acids 180
Annotations 0
Features 15
PDB binders 0
Druggability 0.367

Overview

Basic information about this protein and its source genome.

Accession
KP13_04356
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44913.1
Status
annotated
Amino acids
180
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
85.93

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.367
Structure A0A0H3GS07
Pocket Pocket 2
P2Rank
Structure A0A0H3GS07
Pocket No pockets
ColabFold model
FPocket 0.391 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 34 / 4744 genomes with a hit
Normalized 0.007

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
1 26 Phobius SIGNAL_PEPTIDE Signal peptide region
22 26 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
47 163 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113
47 163 InterPro IPR017734 Type VI secretion system, lipoprotein SciN
1 26 SignalP_EUK SignalP-noTM SignalP-noTM
9 177 PANTHER PTHR37625 OUTER MEMBRANE LIPOPROTEIN-RELATED
9 177 InterPro IPR017734 Type VI secretion system, lipoprotein SciN
44 180 Gene3D G3DSA:2.60.40.4150 Type VI secretion system, lipoprotein SciN
44 180 InterPro IPR038706 Type VI secretion protein SciN-like superfamily
1 19 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
12 163 NCBIfam TIGR03352 type VI secretion system lipoprotein TssJ
12 163 InterPro IPR017734 Type VI secretion system, lipoprotein SciN
10 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
27 180 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 9 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GS07
AlphaFold — — full sequence — Viewing
ColabFold KP13_04356
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.367