Protein profile

KP13_04353

hypothetical protein

Genome: KpKP13

Gene: AHE44916.1 Structure source: AlphaFold + ColabFold UniProt A0A6A8EL11
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Amino acids 530
Annotations 0
Features 7
PDB binders 0
Druggability 0.429

Overview

Basic information about this protein and its source genome.

Accession
KP13_04353
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44916.1
Status
annotated
Amino acids
530
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
89.0

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.429
Structure A0A6A8EL11
Pocket Pocket 17
P2Rank 0.41
Structure A0A6A8EL11
Pocket Pocket 1
ColabFold model
FPocket 0.436 · Pocket 1
P2Rank 0.329 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 61 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
33 128 Pfam PF06812 ImpA, N-terminal, type VI secretion system
33 128 InterPro IPR010657 ImpA, N-terminal
20 487 PANTHER PTHR37024 TYPE VI SECRETION SYSTEM DUF2094 AND IMPA-RELATED DOMAIN PROTEIN
228 487 Pfam PF16989 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ
228 487 InterPro IPR017739 Type VI secretion system-associated, VCA0119
29 487 NCBIfam TIGR03362 type VI secretion system protein TssA
29 487 InterPro IPR017739 Type VI secretion system-associated, VCA0119

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A6A8EL11
AlphaFold — — full sequence — Viewing
ColabFold KP13_04353
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
17 0.429
4 0.316
2 0.21

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.7 0.34
2 1.98 0.042
3 1.17 0.009
4 0.91 0.004