Protein profile

KP13_04349

hypothetical protein

Genome: KpKP13

Gene: AHE44920.1 Structure source: AlphaFold + ColabFold UniProt A0A486RIH0
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Amino acids 599
Annotations 0
Features 6
PDB binders 0
Druggability 0.46

Overview

Basic information about this protein and its source genome.

Accession
KP13_04349
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44920.1
Status
annotated
Amino acids
599
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
84.55

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.46
Structure A0A486RIH0
Pocket Pocket 1
P2Rank 0.479
Structure A0A486RIH0
Pocket Pocket 1
ColabFold model
FPocket 0.648 · Pocket 5
P2Rank 0.632 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 8 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
493 513 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
514 599 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
70 195 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235)
70 195 InterPro IPR018712 Tle1 phospholipase
1 492 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
24 246 PANTHER PTHR33840 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A486RIH0
AlphaFold — — full sequence — Viewing
ColabFold KP13_04349
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.46
9 0.404
24 0.272

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.53 0.33
2 6.32 0.317
3 5.28 0.247
4 4.19 0.171
5 3.06 0.102