Protein profile

KP13_32214

putative lipoprotein

Genome: KpKP13

Gene: AHE44922.1 Structure source: AlphaFold + ColabFold UniProt A0A6A8EK96
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Amino acids 197
Annotations 0
Features 12
PDB binders 0
Druggability 0.568

Overview

Basic information about this protein and its source genome.

Accession
KP13_32214
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44922.1
Status
annotated
Amino acids
197
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
88.01

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.568
Structure A0A6A8EK96
Pocket Pocket 1
P2Rank 0.078
Structure A0A6A8EK96
Pocket Pocket 1
ColabFold model
FPocket 0.294 · Pocket 2
P2Rank 0.04 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 15 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 26 Phobius SIGNAL_PEPTIDE Signal peptide region
1 19 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
5 16 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
119 139 Coils Coil Coil
17 26 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 26 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
37 169 Pfam PF11745 Protein of unknown function (DUF3304)
37 169 InterPro IPR021733 Protein of unknown function DUF3304
27 197 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 20 SignalP_EUK SignalP-noTM SignalP-noTM
1 26 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A6A8EK96
AlphaFold — — full sequence — Viewing
ColabFold KP13_32214
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.568
2 0.389
7 0.356
14 0.331