Protein profile

KP13_03060

putative Type VI secretion system protein

Genome: KpKP13

Gene: AHE44932.1 Structure source: AlphaFold + ColabFold UniProt W8ULC0
Export view
Amino acids 195
Annotations 0
Features 8
PDB binders 0
Druggability 0.911

Overview

Basic information about this protein and its source genome.

Accession
KP13_03060
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44932.1
Status
annotated
Amino acids
195
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
76.23

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.911
Structure W8ULC0
Pocket Pocket 8
P2Rank 0.13
Structure W8ULC0
Pocket Pocket 1
ColabFold model
FPocket 0.509 · Pocket 16
P2Rank 0.099 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 71 / 4744 genomes with a hit
Normalized 0.015

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
34 193 PANTHER PTHR35850 CYTOPLASMIC PROTEIN-RELATED
34 193 InterPro IPR008312 Type VI secretion system sheath protein TssB1
30 195 PIRSF PIRSF028301 UCP028301
30 195 InterPro IPR008312 Type VI secretion system sheath protein TssB1
37 190 NCBIfam TIGR03358 type VI secretion system contractile sheath small subunit
37 190 InterPro IPR008312 Type VI secretion system sheath protein TssB1
39 189 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2
39 189 InterPro IPR008312 Type VI secretion system sheath protein TssB1

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_W8ULC0
AlphaFold — — full sequence — Viewing
ColabFold KP13_03060
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
8 0.911
15 0.21

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 5.06 0.231
2 1.21 0.011