Protein profile

KP13_31588

putative alpha/beta-Hydrolases superfamily protein

Genome: KpKP13

Gene: AHE44942.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GM47
Export view
Amino acids 378
Annotations 0
Features 13
PDB binders 0
Druggability 0.165

Overview

Basic information about this protein and its source genome.

Accession
KP13_31588
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE44942.1
Status
annotated
Amino acids
378
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
91.64

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.165
Structure A0A0H3GM47
Pocket Pocket 1
P2Rank 0.889
Structure A0A0H3GM47
Pocket Pocket 1
ColabFold model
FPocket 0.129 · Pocket 1
P2Rank 0.912 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 799 / 4744 genomes with a hit
Normalized 0.168

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
31 378 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
195 305 Gene3D G3DSA:1.10.10.800 -
31 378 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
31 378 InterPro IPR029058 Alpha/Beta hydrolase fold
8 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 30 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 30 Phobius SIGNAL_PEPTIDE Signal peptide region
58 373 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
58 373 InterPro IPR029058 Alpha/Beta hydrolase fold
1 30 SignalP_EUK SignalP-noTM SignalP-noTM
19 30 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
43 377 PANTHER PTHR47751 SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GM47
AlphaFold — — full sequence — Viewing
ColabFold KP13_31588
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 20.92 0.864
2 0.85 0.003