Protein profile

KP13_05448

Phage shock protein A

Genome: KpKP13

Gene: pspA AHE44962.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GRR1
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Amino acids 233
Annotations 0
Features 9
PDB binders 0
Druggability 0.762

Overview

Basic information about this protein and its source genome.

Accession
KP13_05448
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
pspA AHE44962.1
Status
annotated
Amino acids
233
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
59.174
DEG E-value
7.230000000000001e-86
Localization
CytoplasmicMembrane
ColabFold pLDDT
82.72

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.762
Structure A0A0H3GRR1
Pocket Pocket 7
P2Rank
Structure A0A0H3GRR1
Pocket No pockets
ColabFold model
FPocket 0.95 · Pocket 3
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 107 / 4744 genomes with a hit
Normalized 0.023

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
58 92 Coils Coil Coil
12 231 PANTHER PTHR31088 MEMBRANE-ASSOCIATED PROTEIN VIPP1, CHLOROPLASTIC
12 231 InterPro IPR007157 PspA/IM30
13 227 Pfam PF04012 PspA/IM30 family
13 227 InterPro IPR007157 PspA/IM30
12 230 NCBIfam TIGR02977 phage shock protein PspA
12 230 InterPro IPR014319 Phage shock protein, PspA
98 153 Coils Coil Coil
172 192 Coils Coil Coil

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GRR1
AlphaFold — — full sequence — Viewing
ColabFold KP13_05448
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
7 0.762