Protein profile

KP13_04090

hypothetical protein

Genome: KpKP13

Gene: AHE45106.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GRD7
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Amino acids 87
Annotations 0
Features 12
PDB binders 0
Druggability 0.658

Overview

Basic information about this protein and its source genome.

Accession
KP13_04090
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45106.1
Status
annotated
Amino acids
87
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
56.977
DEG E-value
1.1000000000000002e-28
Localization
CytoplasmicMembrane
ColabFold pLDDT
88.45

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.658
Structure A0A0H3GRD7
Pocket Pocket 1
P2Rank 0.01
Structure A0A0H3GRD7
Pocket Pocket 1
ColabFold model
FPocket 0.71 · Pocket 3
P2Rank 0.003 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 40 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
4 84 Pfam PF10749 Protein of unknown function (DUF2534)
4 84 InterPro IPR019685 Protein of unknown function DUF2534
33 55 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
17 39 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 33 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
59 81 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
28 32 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
56 81 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
16 27 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
82 87 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
1 15 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 32 Phobius SIGNAL_PEPTIDE Signal peptide region

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GRD7
AlphaFold — — full sequence — Viewing
ColabFold KP13_04090
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.658

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.04 0.006