Protein profile

KP13_04035

Gp17 phage protein

Genome: KpKP13

Gene: AHE45165.1 Structure source: AlphaFold + ColabFold UniProt A0AAX2BQN4
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Amino acids 251
Annotations 4
Features 4
PDB binders 0
Druggability 0.866

Overview

Basic information about this protein and its source genome.

Accession
KP13_04035
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45165.1
Status
annotated
Amino acids
251
Structure source
AlphaFold + ColabFold
GO
GO:0046718 The process by which a symbiont breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the symbiont or its genome is released into the host cell. GO:0098015 Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell. GO:0030430 The cytoplasm of a host cell. GO:0051536 Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
87.95

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.866
Structure A0AAX2BQN4
Pocket Pocket 4
P2Rank 0.57
Structure A0AAX2BQN4
Pocket Pocket 1
ColabFold model
FPocket 0.28 · Pocket 3
P2Rank 0.196 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 37 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4
  • GO:0046718 The process by which a symbiont breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the symbiont or its genome is released into the host cell.
  • GO:0098015 Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell.
  • GO:0030430 The cytoplasm of a host cell.
  • GO:0051536 Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
7 247 NCBIfam TIGR01600 phage minor tail protein L
7 247 InterPro IPR006487 Bacteriophage lambda, Tail tip protein L
26 248 Pfam PF05100 Phage minor tail protein L
26 248 InterPro IPR006487 Bacteriophage lambda, Tail tip protein L

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0AAX2BQN4
AlphaFold — — full sequence — Viewing
ColabFold KP13_04035
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.866

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 11.76 0.624
2 3.18 0.109