Protein profile

KP13_04007

hypothetical protein

Genome: KpKP13

Gene: AHE45196.1 Structure source: AlphaFold + ColabFold UniProt A0A486N9X9
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Amino acids 343
Annotations 0
Features 4
PDB binders 0
Druggability 0.228

Overview

Basic information about this protein and its source genome.

Accession
KP13_04007
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45196.1
Status
annotated
Amino acids
343
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
87.09

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.228
Structure A0A486N9X9
Pocket Pocket 17
P2Rank 0.075
Structure A0A486N9X9
Pocket Pocket 1
ColabFold model
FPocket 0.105 · Pocket 19
P2Rank 0.049 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 17 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
250 312 CDD cd00085 HNHc
250 312 InterPro IPR003615 HNH nuclease
161 340 Pfam PF06147 Protein of unknown function (DUF968)
161 340 InterPro IPR010373 Protein of unknown function DUF968

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A486N9X9
AlphaFold — — full sequence — Viewing
ColabFold KP13_04007
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
17 0.228

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.85 0.036
2 1.65 0.027