Protein profile

KP13_04003

DNA-damage-inducible protein I

Genome: KpKP13

Gene: AHE45199.1 dinI Structure source: AlphaFold + ColabFold UniProt A0A2Z6EKA7
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Amino acids 77
Annotations 1
Features 8
PDB binders 0
Druggability 0.724

Overview

Basic information about this protein and its source genome.

Accession
KP13_04003
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45199.1 dinI
Status
annotated
Amino acids
77
Structure source
AlphaFold + ColabFold
GO
GO:0009432 An error-prone process for repairing damaged microbial DNA.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
93.6

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.724
Structure A0A2Z6EKA7
Pocket Pocket 1
P2Rank
Structure A0A2Z6EKA7
Pocket No pockets
ColabFold model
FPocket 0.437 · Pocket 2
P2Rank 0.053 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 35 / 4744 genomes with a hit
Normalized 0.007

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0009432 An error-prone process for repairing damaged microbial DNA.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
1 77 Gene3D G3DSA:3.30.910.10 -
1 77 InterPro IPR036687 DinI-like superfamily
1 76 SUPERFAMILY SSF54857 DNA damage-inducible protein DinI
1 76 InterPro IPR036687 DinI-like superfamily
1 76 PANTHER PTHR36572 DNA DAMAGE-INDUCIBLE PROTEIN I-RELATED
1 76 InterPro IPR010391 DNA damage-inducible protein DinI-like
14 76 Pfam PF06183 DinI-like family
14 76 InterPro IPR010391 DNA damage-inducible protein DinI-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A2Z6EKA7
AlphaFold — — full sequence — Viewing
ColabFold KP13_04003
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.724