Protein profile

KP13_04931

hypothetical protein

Genome: KpKP13

Gene: AHE45294.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GVG6
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Amino acids 217
Annotations 0
Features 16
PDB binders 0
Druggability 0.338

Overview

Basic information about this protein and its source genome.

Accession
KP13_04931
Assembly
Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence
Gene
AHE45294.1
Status
annotated
Amino acids
217
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
89.38

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.338
Structure A0A0H3GVG6
Pocket Pocket 10
P2Rank 0.21
Structure A0A0H3GVG6
Pocket Pocket 1
ColabFold model
FPocket 0.363 · Pocket 9
P2Rank 0.345 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 105 / 4744 genomes with a hit
Normalized 0.022

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
1 94 Gene3D G3DSA:1.10.10.10 -
1 94 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
1 94 FunFam G3DSA:1.10.10.10:FF:000196 UPF0502 protein YceH
95 175 Gene3D G3DSA:1.10.10.10 -
95 175 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
5 213 Hamap MF_01584 UPF0502 protein YceH [yceH].
5 213 InterPro IPR007432 Protein of unknown function DUF480
1 215 PANTHER PTHR38768 UPF0502 PROTEIN YCEH
1 215 InterPro IPR007432 Protein of unknown function DUF480
5 158 Pfam PF04337 Protein of unknown function, DUF480
5 158 InterPro IPR007432 Protein of unknown function DUF480
187 214 Coils Coil Coil
90 172 SUPERFAMILY SSF46785 Winged helix DNA-binding domain
90 172 InterPro IPR036390 Winged helix DNA-binding domain superfamily
2 84 SUPERFAMILY SSF46785 Winged helix DNA-binding domain
2 84 InterPro IPR036390 Winged helix DNA-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GVG6
AlphaFold — — full sequence — Viewing
ColabFold KP13_04931
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
10 0.338
11 0.256

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.86 0.151