Overview
Basic information about this protein and its source genome.
- Accession
- KP13_04179
- Gene
- AHE45410.1
- Status
- annotated
- Amino acids
- 420
- Structure source
- AlphaFold + ColabFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Human identity (%)
- 0.0
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- DEG identity (%)
- 0.0
- Localization
- Cytoplasmic
- ColabFold pLDDT
- 90.16
Selected Druggability evidence
AlphaFold / UniProt modelSelected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 4 | 418 | Pfam | PF13701 | Transposase DDE domain group 1 |
| 4 | 418 | InterPro | IPR025668 | Transposase DDE domain |
| 4 | 408 | NCBIfam | NF033539 | IS1380 family transposase |
| 86 | 367 | SUPERFAMILY | SSF53098 | Ribonuclease H-like |
| 86 | 367 | InterPro | IPR012337 | Ribonuclease H-like superfamily |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 2Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
AF_A0A0H3GPI0
|
AlphaFold | — | — | full sequence | — | Viewing |
|
ColabFold
KP13_04179
|
ColabFold | — | — | full sequence | — | Loaded |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (P2RANK)
Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).
| P2RANK | Sticks | Spheres | Surfaces | Score | Probability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|---|
| 1 | 4.67 | 0.203 | ||||||
| 2 | 3.79 | 0.146 | ||||||
| 3 | 1.6 | 0.025 | ||||||
| 4 | 1.26 | 0.012 | ||||||
| 5 | 0.89 | 0.004 |
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 1 | 0.872 | ||||||
| 7 | 0.473 |
Pockets (P2RANK)
Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).
| P2RANK | Sticks | Spheres | Surfaces | Score | Probability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|---|
| 1 | 5.05 | 0.23 | ||||||
| 2 | 2.09 | 0.047 | ||||||
| 3 | 1.81 | 0.034 | ||||||
| 4 | 1.51 | 0.022 | ||||||
| 5 | 1.14 | 0.009 |